E	Error	The document is required in the sequence being submitted. If no document is present, it will lead to a validation error and the sequence being rejected.
W	Warning	The document is expected in the sequence. If no document is present, it will lead to a warning and could possibly lead to the sequence being rejected.
P	Possible	The document is required in certain circumstances for the particular sequence type, but not all. A list of the sections where content has been provided will be created by the validator for review purposes in content screening. The absence of a required document could lead to the sequence being rejected.
XE	Excluded: Error	The document is not allowed for the particular Submission Type and will result in an Error if included.
XW	Excluded: Warning	The document is not expected for the particular Submission Type and will result in a Warning if included.
NV	Not Validated	The presence or absence of the document is not checked in the electronic validation of the particular Sequence Type.
	Not Yet Defined	Not yet planned within the scope of the eCTD.